320 results
CARDIAC MYOCYTE POTENTIALS

#Pathophysiology #Cardiology #Cardiac #Myocyte #Ventricular #ActionPotentials #Channels #Phases
CARDIAC MYOCYTE ... Cardiology #Cardiac #Myocyte
Action potential in cardiomyocytes
The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning
Depolarization Phase 1: ... ActionPotential #Myocytes
Cardiac Myocyte Contractile cycle
 - Ca2+ binds to TnC → TnI is inhibited → conformational change
Cardiac Myocyte ... Pathophysiology #Cardiology #Myocyte
Cardiomyopathies 

Manifestations of cardiomyopathy (CM) range from microscopic alterations in cardiac myocytes to fulminant Heart Failure
alterations in cardiac myocytes
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Cardiac: • Myocyte
Gout Management in CKD
 • Colchicine
 • NSAID
 • Glucocorticoid
 • ACTH
 • Interleukin-1 Inhibitors

#Gout #Management
• Interleukin-1 ... #rheumatology #treatment
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
Treatment of hyperkalemia ... kaliuresis step 1 ... #criticalcare #treatment
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity Treatment ... : 1) Hydroxocobalamin ... Pathophysiology #Management #Treatment
Hyponatremia Treatment Algorithm

CHF, Cirrhosis - Fluid restriction
SIADH - Fluid restriction
 - Consider salt tablets if etiology
Hyponatremia Treatment ... Reset Osmostat - Treatment ... water diuresis) 1° ... #Hyponatremia #Treatment
Hepatorenal Syndrome Treatment
Volume expansion: 
 • Albumin (typical dose = 1g/kg on day 1 +/- day
Hepatorenal Syndrome Treatment ... = 1g/kg on day 1 ... Midodrine - An alpha- 1 ... Hepatorenal #Syndrome #Treatment