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diagnosis differential causes algorithm management clinical rheumatology pathophysiology dermatology neurology signs gastroenterology symptoms disease treatment table comparison hematology syndrome msk
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... #Inflammatory ... #myopathies #Dermatomyositis ... #Hypothyroid myopathy ... Statin-induced myopathy
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory ... Myopathies - ... Dermatomyositis ... TerrierBen #Inflammatory ... #Myopathy #Comparison
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Critical Illness Myopathy ... - Metabolic Myopathies ... toxoplasmosis - Inflammatory ... myopathy: dermatomyositis ... polymyositis, necrotizing myopathy
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
Systemic Findings in Dermatomyositis ... - Symmetric, inflammatory ... myopathy (Triceps ... Arrhythmias - Inflammatory ... Findings #Signs #Dermatomyositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Myoglobinuria DDX: • Inflammatory ... , toxic myopathy ... polymyositis, dermatomyositis ... Statins → Inflammatory ... : Inflammatory statin
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... Dermatomyositis ... BrighamChiefs #Inflammatory ... #Myopathies #differential
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
spinal cord • Inflammatory ... Paraneoplastic syndrome • Inflammatory ... : • Inflammatory ... • Metabolic myopathies ... Muscle Biopsy: Dermatomyositis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnosis Framework Inflammatory ... levels • EMG DERMATOMYOSITIS ... dermatomyositis ... of the time) Dermatomyositis ... association with dermatomyositis
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Anti-Jo, +Anti-Mi2 Dermatomyositis ... load Drug-induced myopathy ... 5-15% of lupus myopathy ... #myopathy #differential
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
That May Mimic Inflammatory ... Myopathy • Central ... • Metabolic myopathies ... Mitochondrial myopathy ... MuscleWeakness #Myopathy
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