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diagnosis differential algorithm neurology endocrinology myopathy rheumatology clinical management pathophysiology weakness dermatology inflammatory physicalexam comparison dermatomyositis hypothyroidism rhabdomyolysis signs symptoms
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... #Inflammatory #myopathies ... Fibromyalgia #Hypothyroid ... myopathy #Muscle ... #Drug-induced myopathies
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory Myopathies ... Immune-Mediated Necrotizing Myopathy ... #Inflammatory #Myopathies ... #Idiopathic #Myopathy
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Causes of Proximal ... Mimic Inflammatory Myopathy ... • Metabolic myopathies ... Mitochondrial myopathy ... #differential #causes
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... load Drug-induced myopathy ... 5-15% of lupus myopathy ... BostonChiefs #Myositis #Myopathies ... #myopathy #differential
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Critical Illness Myopathy ... Subacute to Chronic Causes ... - Metabolic Myopathies ... - Inflammatory myopathy
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... , hypothyroid-induced ... → Inflammatory myopathies ... Statin-induced myopathy ... - Necrotizing myopathy
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
proximal weakness Myopathy ... mediated necrotizing myopathy ... Endocrinopathies: Hypothyroid ... • Metabolic myopathies ... certain drug-induced myopathies
Causes of Orthopnea - Differential Diagnosis Framework • Fear and Anxiety • Pleural Effusion • Ascites
Causes of Orthopnea ... GBS, CIDP - Myopathies ... Differential #Diagnosis #Causes
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Idiopathic Inflammatory Myopathies ... idiopathic inflammatory myopathies ... Any inflammatory myopathy ... Inflammatory myopathy ... #Inflammatory #Myopathies
Waddling (Myopathic) Gait on Physical Exam Myopathic gait, also known as waddling gait, is caused by muscle
Waddling (Myopathic ... Physical Exam Myopathic ... waddling gait, is caused ... #Waddling #Myopathic
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