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diagnosis neurology differential clinical physicalexam video algorithm management signs symptoms causes msk pathophysiology endocrinology orthopedics rheumatology treatment sign syndrome pediatrics
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... #Inflammatory #myopathies ... Dermatomyositis #muscle weakness ... #Hypothyroid myopathy ... #Drug-induced myopathies
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Idiopathic Inflammatory Myopathies ... RASH + MUSCLE WEAKNESS ... idiopathic inflammatory myopathies ... Severe proximal weakness ... #Inflammatory #Myopathies
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... symmetric muscle weakness ... symmetric muscle weakness ... Fever, No muscle weakness ... BostonChiefs #Myositis #Myopathies
Waddling (Myopathic) Gait on Physical Exam Myopathic gait, also known as waddling gait, is caused by muscle
Waddling (Myopathic ... Physical Exam Myopathic ... caused by muscle weakness ... #Waddling #Myopathic
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 Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Proximal Muscle Weakness ... Mimic Inflammatory Myopathy ... • Metabolic myopathies ... Mitochondrial myopathy ... MuscleWeakness #Myopathy
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Elevation (Pain > Weakness ... Critical Illness Myopathy ... Chronic Causes (Weakness ... PROXIMAL MUSCLE WEAKNESS ... - Metabolic Myopathies
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Myopathy: ... mediated necrotizing myopathy ... • Metabolic myopathies ... certain drug-induced myopathies
Causes of Orthopnea - Differential Diagnosis Framework • Fear and Anxiety • Pleural Effusion • Ascites
Diaphragmatic weakness ... GBS, CIDP - Myopathies
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... • Inflammatory myopathy ... → Inflammatory myopathies ... Statin-induced myopathy
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... Associated Features: Weakness ... #Inflammatory #Myopathies
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