29 results
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory Myopathies ... Immune-Mediated Necrotizing Myopathy ... #Idiopathic #Myopathy ... Managment #algorithm #Rheumatology ... #Differential
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
#ESR #CK #Differential ... diagnosis of myopathy ... #Hypothyroid myopathy ... Statin-induced myopathy ... Cocaine-induced myopathy
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
rimmed vacuoles HIV myopathy ... load Drug-induced myopathy ... Gemcitabine Lupus Myopathy ... 5-15% of lupus myopathy ... #myopathy #differential
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Mimic Inflammatory Myopathy ... • Metabolic myopathies ... Mitochondrial myopathy ... MuscleWeakness #Myopathy ... mimics #diagnosis #differential
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Critical Illness Myopathy ... - Metabolic Myopathies ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy ... #Elevated #CK #differential
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Inflammatory Arthritis - Differential ... , Inflammatory Myopathy ... #arthritides #Differential ... #Diagnosis #rheumatology
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Idiopathic Inflammatory Myopathies ... Any inflammatory myopathy ... Inflammatory myopathy ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... and anti-HMGCR myopathy ... Myositis #diagnosis #rheumatology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Mediated Necrotizing Myopathy ... clinical #diagnosis #rheumatology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Sensory Changes - Differential ... Oculomotor • Myopathy ... Sensory #Neurology #Differential