22 results
differential neurology rheumatology algorithm causes management chestpain myositis acutecoronarysyndrome angina atypical autoimmune cardiac idiopathic inflammatory likelihoodratios lr myopathies nephrology rhabdomyolysis
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... (ASS), Inclusion ... Body Myositis (IBM ... #Idiopathic #Myopathy
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... such as • Statin-induced ... Atorvastatin Diagnosis ... #diagnosis #management
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Critical Illness Myopathy ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy ... #differential #diagnosis
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Any inflammatory myopathy ... antisynthetase syndrome ... Inflammatory myopathy ... #IIMs #diagnosis ... #dermatology #Myopathy
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Motor Nerves: ALS ... Guillain-Barre syndrome ... Mitochondrial myopathy ... #differential #diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... Myopathy: ... mediated necrotizing myopathy ... Coxsackie, HIV, CMV, EBV ... #Differential #Diagnosis
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... - Differential Diagnosis ... Infectious: Influenza, EBV ... I am weak": • Myopathy ... Polyneuropathy, ALS
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... /full triad at diagnosis ... and anti-HMGCR myopathy
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... Body Myositis (IBM ... MSAs #clinical #diagnosis ... #rheumatology #table
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. Source: Does This
Acute Coronary Syndrome ... - Diagnostic Likelihood ... Acute Coronary Syndrome ... #EBM #Diagnosis ... #Cardiology #ACS
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