285 results
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... #Idiopathic #Myopathy ... Comparison #Managment #algorithm ... #Rheumatology #Differential
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
#ESR #CK #Differential ... diagnosis of myopathy ... #Hypothyroid myopathy ... Statin-induced myopathy ... Cocaine-induced myopathy
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... MuscleWeakness #Myopathy ... #mimics #diagnosis ... #differential #
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
load Drug-induced myopathy ... Gemcitabine Lupus Myopathy ... 5-15% of lupus myopathy ... #myopathy #differential ... #diagnosis #comparison
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... Statin-induced myopathy ... - Necrotizing myopathy ... Atorvastatin Diagnosis ... #diagnosis #management
Abdominal Distention - Differential Diagnostic Algorithm
Ascites
Bowel Dilatation
Other Causes
Mechanical Obstruction
 • Adhesions 60%
 • Volvulus 3%
 •
Diagnostic Algorithm ... Intestinal Ogilvie's Syndrome ... • Ischemic Myopathic ... Scleroderma • Familial Myopathy ... #Diagnosis #Algorithm
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Critical Illness Myopathy ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Sensory Changes - Differential ... Diagnosis Algorithm ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Diagnosis #Algorithm
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Sensory Changes - Differential ... Diagnosis Algorithm ... Oculomotor • Myopathy ... Sensory #Neurology #Differential ... #Diagnosis #Algorithm
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
, Orbital apex syndrome ... Miller-Fisher syndrome ... sclerosis, Thyroid myopathy ... mass #Diplopia #differential ... #diagnosis #ophthalmology