21 results
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... #Idiopathic #Myopathy ... #Comparison #Managment ... #algorithm #Rheumatology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... hypothyroid-induced myopathy ... Statin-induced myopathy ... - Necrotizing myopathy ... #diagnosis #management
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Any inflammatory myopathy ... antisynthetase syndrome ... Inflammatory myopathy ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... anti-synthetase syndrome ... and anti-HMGCR myopathy ... Myositis #diagnosis #rheumatology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... clinical #diagnosis #rheumatology
Ashkenazi Jewish Genetic Screening Algorithm
 • Bloom syndrome
 • Canavan disease
 • Familial dysautonomia
 • Fanconi
Genetic Screening Algorithm ... • Bloom syndrome ... 1A • Joubert syndrome ... NEB-related nemaline myopathy ... Genetic #Screening #Algorithm
Abdominal Distention - Differential Diagnostic Algorithm
Ascites
Bowel Dilatation
Other Causes
Mechanical Obstruction
 • Adhesions 60%
 • Volvulus 3%
 •
Differential Diagnostic Algorithm ... Intestinal Ogilvie's Syndrome ... • Ischemic Myopathic ... Scleroderma • Familial Myopathy ... Differential #Diagnosis #Algorithm
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Differential Diagnosis Algorithm ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... Differential #Diagnosis #Algorithm
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... and Treatment Algorithm ... #HES #Hematology ... eosinophils #diagnosis #management ... #algorithm
Acute Coronary Syndrome - Management Algorithm
 • STEMI
 • NSTEMI (Troponin Positive) / Unstable Angina (UA,
Acute Coronary Syndrome ... - Management Algorithm ... Acute #Coronary #Syndrome ... #ACS #Management ... #Algorithm #cardiology