126 results
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
Hypothyroidism is a clinical ... syndrome resulting ... and scaly skin, myopathy ... Myopathy due to ... #video #neurology
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
think about three clinical ... Neurogenic Ptosis - Neurologic ... Mitochondrial myopathy ... gravis • Ocular myopathy ... #Ptosis #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Differential Diagnosis Neurologic-Centered ... late-onset nemaline myopathy ... capillary leak syndrome ... • Schnitzler syndrome
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory Myopathies ... Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... #Inflammatory #Myopathies ... #Idiopathic #Myopathy
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Mimic Inflammatory Myopathy ... or peripheral neurologic ... Mitochondrial myopathy ... MuscleWeakness #Myopathy ... differential #causes #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... • Inflammatory myopathy ... Statin-induced myopathy ... - Necrotizing myopathy ... IU/I • SAMS clinical
Neurological Patterns of Weakness
 • Hemispheric lesion
 • Brainstem lesion
 • Spinal cord lesion
 • Polyneuropathy
Polyneuropathy • Myopathy ... #Neurology #Patterns
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
immobility • Critical ... Illness Myopathy ... - Metabolic Myopathies ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... proximal weakness Myopathy ... mediated necrotizing myopathy ... Differential #Diagnosis #neurology
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Idiopathic Inflammatory Myopathies ... Any inflammatory myopathy ... antisynthetase syndrome ... Inflammatory myopathy ... #dermatology #Myopathy