81 results
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... and scaly skin, myopathy ... Myopathy due to ... (shown in the video ... #neurology #endocrinology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory Myopathies ... Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... #Inflammatory #Myopathies ... #Idiopathic #Myopathy
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Mimic Inflammatory Myopathy ... or peripheral neurologic ... Mitochondrial myopathy ... MuscleWeakness #Myopathy ... differential #causes #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... hypothyroid-induced myopathy ... Statin-induced myopathy ... - Necrotizing myopathy ... fibers Risk of myopathy
Neurological Patterns of Weakness
 • Hemispheric lesion
 • Brainstem lesion
 • Spinal cord lesion
 • Polyneuropathy
Polyneuropathy • Myopathy ... #Neurology #Patterns
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... proximal weakness Myopathy ... mediated necrotizing myopathy ... Differential #Diagnosis #neurology
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Idiopathic Inflammatory Myopathies ... Any inflammatory myopathy ... antisynthetase syndrome ... Inflammatory myopathy ... #dermatology #Myopathy
Waddling (Myopathic) Gait on Physical Exam

Myopathic gait, also known as waddling gait, is caused by muscle
Waddling (Myopathic ... Physical Exam Myopathic ... #Waddling #Myopathic ... PhysicalExam #clinical #video ... #neurology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... anti-synthetase syndrome ... and anti-HMGCR myopathy
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy ... differential #diagnosis #neurology