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diagnosis disease erythematosus lupus sle syndrome anca antibody antineutrophil antinxp2 antinxp2dm behcet dermatology dermatomyositis diseases fungal igg4 infections infectiousdiseases mycoses
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... drug-induced SLE) • Systemic ... scleroderma) - Anti-Scl ... #rheumatology #
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... (ANA) - 95% - Initial ... severe disease & renal ... Summary #diagnosis #rheumatology ... #management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
female, asian • Systemic ... autoantibodies (antinuclear ... antibodies, rheumatoid ... Disease #diagnosis #management ... workup #treatment #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... antibodies ≥ 1: ... Central nervous system ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... disease (panuveitis, retinal ... Ocular: Giant retinal ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... -70, RNP antibodies ... anticardiolipin antibodies
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... dorsal part of the MCP ... • Clear cell renal ... Dermatomyositis #diagnosis #management ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... for Blastomyces antibodies ... the circulatory system ... for Coccidioides antibodies ... Fungal #Diagnosis #Management
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