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diagnosis nephrology differential management algorithm causes hypokalemia defects potassium secondary alkalosis chloride comparison encephalopathy epithelial familial fanconi indications inheritable inherited
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Proximal tubule Bartter ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Pocket Comparison Guide to Heritable Hypertension Syndromes (Secondary Hypertension) Bartter, Gitelman, Liddle, Primary Aldosteronism, GRA (Glucocorticoid Remediable
Syndromes (Secondary ... Hypertension) ... Bartter, Gitelman ... #Syndromes #Comparison ... #Table #Diagnosis
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Diagnosis Algorithm Hypertensive ... acid, Liddle's Syndrome ... h - Diuretics, Bartter's ... syndrome, Gitelman's ... Diagnosis #Algorithm #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
acid transporter Bartter ... syndrome - Na-K ... ascending limb Gitelman ... Defects #Kidney #Nephrology ... #Differential #Table
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
the existence of hypertension ... • Diuretics, Bartter's ... syndrome, Gitelman's ... syndrome • Primary ... algorithm #causes #nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
- Workup and Differential ... with previously stable ... heart failure, neurologic ... Neurologic disorders ... #Workup #causes
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Vision changes • Hypertensive ... may precede the neurologic ... /Hypertensive emergency ... Etiology: • Pathophysiology ... diagnosis #management #neurology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia ... • Hypertension ... urine #Algorithm #nephrology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... Pathophysiology ... antibody that works ... spondylitis, Axial dystonia ... Management #treatment #neurology
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