267 results
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
N-Acetyl Cysteine (NAC ... NAC helps replenish ... Figure 2.1 NAC has ... GSH) precursor, NAC3 ... substitute, and NAC4
#paracetamol #paracetamoloverdose #NAC
paracetamoloverdose #NAC
Addictions: Pathogenesis

Mesolimbic Dopaminergic Pathway:
 • Dopaminergic neurons in Ventral Tegmental Area (VTA) in midbrain under continuous
Nucleus Accumbens (NAc ... ) • The NAC receives ... response) • The NAC
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
N-Acetylcysteine (NAC
Thiazide
diuretics
Carbonic anhydrase
inhibitors
(e.g., acetazolamide)
Nat-Cl symport
Na and HCO;-
reabsorption
Aldosterone
antagonists
(e.g., spironolactone)
Nat channel
(indirect effect)
Loop diuretics (e.g., furosemide)
Amiloride,
#triamterene
Nat-K+-2CF symport
Na channel
(direct effect)
#NaCI reabsorption
acetazolamide) Nat-Cl ... symport Na and ... spironolactone) Nat ... +-2CF symport Na ... direct effect) #NaCI
Fomepizole for Acetaminophen Toxicity

 • In cases where fomepizole and NAC were administered together, evidence has
fomepizole and NAC
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
Enterocolitis (NEC ... • Neutropenia (ANC ... 1min_idconsult #NEC
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC ... Beta-Blockers Decreased Na
The 3 Fates of a Premature Atrial Complex
 • PAC can be conducted with normal QRS
Atrial Complex • PAC ... • PAC can be ... aberrancy - A PAC ... • PAC can be ... non- conducted PAC
Obstetric Ultrasound Pocket Card
1st Trimester Checklist:
 • Look for signs of an IUP
 • Gestational dating
dating • Mean sac ... biometrics: BPD, HC, AC