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Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
inflammation: Increased neutrophils ... Disease #diagnosis #management
“Step by Step” – the new kid on the block – aims to risk stratify this
mL - Absolute Neutrophil ... #Diagnosis #Management
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... Dysplastic neutrophils ... Hypersegmented #neutrophils
How to distinguish a metamyelocyte from a band neutrophil. - Kyle Bradley, MD @KyleBradleyMD #Clinical #Pathology #Microscopy #Blood #Smear
metamyelocyte from a band neutrophil ... Metamyelocytes #Bands #Neutrophils
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... - Increased Neutrophils ... blast cells) #Neutrophilia ... #Increased #Neutrophils
Sweet’s Syndrome - Acute febrile neutrophilic dermatosis The syndrome involves fever, painful rash, neutrophilic leukocytosis, and
Acute febrile neutrophilic ... painful rash, neutrophilic ... leukocytosis, and neutrophil ... Sweets #Syndrome #neutrophilic
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
rash, arthritis, neutrophilic ... rheumatology #diagnosis #management
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
granulocytes (neutrophils ... Neutrophil bands ... : Immature neutrophils ... as significant neutrophilia ... Mature neutrophils
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
acute febrile neutrophilic ... APML #diagnosis #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
> 10% Band neutrophils ... than segmented neutrophils ... Band neutrophils ... in German) • Neutrophils ... Shift) → Segmented Neutrophil
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