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management rheumatology differential lupus sle neurology systemic comparison thrombocytopenia treatment alkaline alp antinxp2 antinxp2dm aspergillus bandemia betadglucan biomarkers cbc cerebritis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Systemic Lupus Erythematosus ... Clinical Domains ... pericarditis • Hematologic ... #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... Disease, PRES Pathophysiology ... permeability Diagnosis ... #cerebritis #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... , macular, patchy ... Differential Diagnosis ... lymphoproliferative syndrome Clinical ... #Diagnosis #Rheumatology
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
Landscaper w/ painless nodular ... wax and wane; diagnosis ... Papulonodular, erythematous ... leishmania, Tb, NTM; less ... Sporotrichiosis #Infection #clinical
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... : • Clinical Suspicion ... titer (ELISA) - ↑Sens ... non-heparin A/C if clinical ... Management #Treatment #Hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... weakness, arms > legs ... myasthenia Diagnosis ... Bedside: ice pack ... Myasthenia #Gravis #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... - Cytopenia - Less ... Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... #diagnosis #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... neutrophils are slightly less ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Adult form: Less ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology ... #diagnosis
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
- Serum BDG: Sens ... infection (IFI) in hematologic ... cut-offs defined in clinical ... - Frozen ice-pops ... Galactomannan #diagnosis
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