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diagnosis betadglucan galactomannan rheumatology treatment aspergillus bcnie behcet biomarkers blood bloodculture candidemia candidiasis comparison disease endocarditis eosinophilia eosinophils falsepositives fungemia
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup and Management ... week to assess ocular ... or TEE unless clinical ... #candida #candidiasis ... #treatment #fungal
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
Simple Virus • Fungal ... : Candida, Cryptococcus ... (Goodpasture's syndrome ... Renal #Transplant #differential ... #blood #urine #management
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... • Pathogens: Candida ... cut-offs defined in clinical ... BAL GM does not differentiate ... - Frozen ice-pops
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... Ocular- 50%: Ptosis ... life-threatening Differential ... Bedside: ice pack ... Gravis #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ulceration • Ocular ... (Clinical Dx). ... Behcet disease) Differential ... #diagnosis #management
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Routine use: Candida ... cut-offs defined in clinical ... >90% (In most clinical ... in BAL does not differentiate ... Penicillium), Frozen ice-pops
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
fastidious bacteria or fungi ... antimicrobials, clinical ... (Aspergillus, Candida ... antiphospholipid syndrome ... Endocarditis #diagnosis #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... skin lesions, ocular ... Parvovirus B19 • Candida ... #Differential # ... Diagnosis #Management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Diagnosis and Management ... than 1500 and clinical ... Infection: helminthic, fungal ... diagnosis #hematology #differential
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... chondritis • Ocular ... ○ Syphilis ○ Fungal ... Diagnosis: • Clinical ... rheumatology #diagnosis #management
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