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diagnosis differential disease signs symptoms syndrome behcet classification criteria erythematosus eularacr fungal gca giantcell gravis infections infectiousdiseases lupus myasthenia mycoses
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... Oral aphthae : SLE ... : SLE, Reactive ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... • Ocular: uveitis ... Prunelle Getten #AdultOnset ... #treatment #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... cutaneous lupus • Arthritis ... least 2 joints • Neurologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... affects the skin, neurologic ... cognitive impairment, neurologic ... vasculitis • Behcet ... Differential #Diagnosis #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... Nice to be confident ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
syndrome, rheumatoid arthritis ... , SLE Myasthenia ... Ocular- 50%: Ptosis ... Gravis #diagnosis #management ... #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Evaluate for NMO, SLE ... Disorders: - SLE ... Myelitis #diagnosis #management ... #neurology #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... gland) biopsy • Ocular ... salivary ducts Clinical ... Arthralgia and Arthritis ... #Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
chondritis • Ocular ... cases such as: • SLE ... Sarcoidosis • Behcet ... Polychondritis #rheumatology ... #diagnosis #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... osteoarticular, pulmonary, ocular ... Meningitis, septic arthritis ... Fungal #Diagnosis #Management
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