31 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
33% of healthy adults ... likely it will be clinically ... Juvenile Idiopathic Arthritis ... Juvenile Idiopathic Arthritis ... #patterns #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... Epidemiology: • Young adults ... : SLE, Reactive ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Fever, Arthralgia/arthritis ... solid cancers • Systemic ... • Ocular: uveitis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... 40, F:M 9:1 • Clinical ... #lupus #Systemic ... #Summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(sJIA) • Adult-onset ... Fever is the main clinical ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Erythematous, macular ... , adult-onset Still ... Non-autoimmune rheumatologic
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
refractory disease Arthritis ... • Azathioprine and ... refractory lesions Ocular ... Syndrome #Treatment #management ... #pharmacology #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... Diagnosis = clinical ... Nice to be confident ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... episode (30%) Systemic ... and chronic synovitis ... Disease #AOSD #rheumatology ... #diagnosis #management