15 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
expression - Age: GCA ... yrs old; F>M Signs ... Anemia - Giant cells ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Scleritis, Heart Disease ... , Rheumatoid Vasculitis ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... and branches • GCA ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... = vasculitis vs ... them, but urgent rheumatology ... #Temporal #Signs ... #Symptoms #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... meningitis), MCC CNS symptoms ... , ulcerative colitis ... #management #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... No necrosis, No vasculitis ... increased IgG4+ cells ... supporting long-term ... workup #treatment #rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... various inflammatory cells ... histopathologic term ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... Vascular: Rheumatoid vasculitis ... Arthritis #RA #Signs ... #Symptoms #diagnosis ... #rheumatology