8 results
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
used on a long-term ... , principal cells ... and intercalated cells ... #Pathophysiology ... NephronRemodeling #NEJM
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Otitis Media: Complications ... to mastoid air cells ... becomes more severe Signs ... #pathophysiology ... #symptoms #signs
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... removal of these cells ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
various inflammatory cells ... histopathologic term ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Bulimia Nervosa: Complications ... also lead to long-term ... BulimiaNervosa #Complications ... #pathophysiology ... #diagnosis #signs