11 results
diagnosis differential algorithm hemolysis causes extravascular intravascular oncology agglutinin classification cold gap globulin hepatitis hepatology hodgkins injury liver lymphoma management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... hemoglobinuria (PNH ... idiopathic) - Autoimmune ... differential #diagnosis #hematology ... #anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... Drug-associated, PCH ... Defects: Sickle cell anemia ... Laboratory Tests ... Differential #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Cold AIHA • Alloimmune ... Cold AIHA • PCH ... • PNH ... anemia • ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
, CKD • Hemolytic ... PK, HbC, HbSS, PNH ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver disease ... Differential #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... platelet decrease - PNH ... elliptocytosis, autoimmune ... #Anemia #Differential ... Algorithm #workup #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... - Mycoplasma, EBV ... • Diagnostic Test ... #hemolytic #anemia ... #hematology #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
HBV, HCV, HEV, EBV ... • Autoimmune: ... Autoimmune hepatitis ... extrahepatic source - Tests ... diagnosis #algorithm #hepatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... WAIHA • CAD • PCH ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... nodosum • Immune hemolytic ... anemia • Pain ... number of sites of disease ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
acute HIV, HBV, EBV ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... differential #diagnosis #hematology
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