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diagnosis differential hemolysis agglutinin algorithm autoimmune causes cold disease hemolytic intravascular myopathy myositis rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Cold AIHA • PCH ... • PNH ... immune-complex hemolytic anemia ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH ... Liver Disease, PNH ... Defects: Sickle cell anemia ... Laboratory Tests ... Differential #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Mycoplasma, EBV ... the RBCs causing intravascular ... • Diagnostic Test ... Donath-Landsteiner test ... #hematology #diagnosis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... • ANA < 20 % IBM ... inflammation • Extramuscular ... Other Diseases: • PBC ... Myositis #Myopathy #rheumatology
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