14 results
Profiles of Antidiabetic Medications - AACE 2018 

#Antidiabetic #Medications #Profiles #SideEffects #Table #DecisionAid #Orals #DM2 #Diabetes
#SideEffects #Table ... DecisionAid #Orals #DM2 ... #Diabetes #Endocrinology ... #Pharmacology #
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
mealtime • If NPO ... #Mellitus #DM2 ... #Medications #pharmacology ... #comparison #table ... #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... #Metformin #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Insulin Comparison Chart

Insulin Types - Onset (hours) - Peak Glycemic Effect (hours) - Duration (hours)
 •
Protamine + Lispro, NPH ... Insulin #Comparison #Table ... #pharmacology # ... diabetes #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
These work by inhibiting ... kidney), which causes ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Ozempic), or daily tablet ... not definitively cause ... #Summary #DM2 # ... diabetes #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... They work primarily ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Uncontrolled diabetes ... Hypomagnesemia #Differential ... Low #Magnesium #Table ... Classification #Causes ... #Workup #hypomg
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 inhibitors work ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology