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NSAID Pharmacology - Amy Chung, MD, MSc @AmyChung #NSAIDs #Pharmacology #COX #Cyclooxygenase
NSAID Pharmacology ... @AmyChung #NSAIDs
NSAID Selectivity Spectrum COX-2 Selective NSAID - Celecoxib • Increased risk for CV events • Decreased risk
NSAID Selectivity ... COX-2 Selective NSAID ... Semiselective NSAIDs ... risk Nonselective NSAIDs ... side effects #NSAIDs
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 NSAID vs ACEI/ARB effects on the Kidneys Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB ... Remember that NSAIDs ... NSAIDs cause vasoconstriction ... kidney function, NSAID ... /ambcarerx #NSAIDs
Summary table of the mechanism of action, side effect and contraindications of commonly used non-steroidal anti-inflammatory
Summary table of ... anti-inflammatory drugs (NSAIDs ... medical diagrams, tables ... #NSAIDS #management ... #pharmacology #table
Anticoagulation Review. There are other bleeding risk assessment tools, but HAS-BLED is more commonly used. HTN
There are other bleeding ... Bleeding includes ... that increase bleeding ... antiplatelets or NSAIDs ... Anticoagulant #Bleeding
Forrest Classification for Peptic Ulcer Bleeding Rebleeding risks are without endoscopic intervention 1a - Spurting Bleed - 60-100%
for Peptic Ulcer Bleeding ... Bleed - 60-100% Re-bleeding ... Bleed - 50% Re-bleeding ... IIa - Non-Bleeding ... Clot - 20-30% Re-bleeding
Adverse Effects of NSAIDs Prostaglandins decreased - Gastric mucosal damage with ulcer formation, bleeding, and perforation -
Adverse Effects of NSAIDs ... ulcer formation, bleeding ... proinflammatory effect #NSAIDs
CERTA Opioid Alternatives Opioid Alternatives for Abdominal Pain (traumatic, non-traumatic), Back Pain, Burns, Renal Colic, Dental Pain,
DO NOT mix NSAID ... Caution with using NSAIDs ... contraindications for NSAID
ED Treatment of Abnormal Uterine Bleeding Hemodynamically unstable Resuscitation • ABCs! • Fluids +
Abnormal Uterine Bleeding ... Hemodynamically stable ... NSAIDs Monophasic ... Abnormal #Uterine #Bleeding
Treatment of Bleeding in Selected Inherited Disorders of Hemostasis #Bleeding #Disorders #HemophiliaA #HemophiliaB #Management #Table #Treatment
Treatment of Bleeding ... Hemostasis #Bleeding ... HemophiliaB #Management #Table
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