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management differential neurology gravis hyperkalemia k lupus manifestations mucocutaneous myasthenia myelitis pathophysiology potassium rheumatology signs symptoms transverse treatment
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... diseases, such as SLE ... purpura: Strong sign ... Multinucleated giant cells ... tract, and often causes
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... : Steroids and NSAIDs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... Evaluate for NMO, SLE ... Pleocytosis > 100 cells ... Disorders: - SLE ... - Sjogren - Vasculitis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+, ACEi/ARBs, NSAIDs ... only if no clear cause ... and Elimination (see ... Drives K+ into cells ... Treatment #potassium #nephrology
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