35 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis vs Primary ... pathophysiology #pbc ... #psc #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... Liver biopsy findings ... #PBC #Primary ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... - Drugs - Primary ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... differential #diagnosis #algorithm ... #hepatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Diabetes Mellitus Liver ... • Cholestatic liver ... Hyperthyroidism CBC ... #generalized #dermatology
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
Algorithm and Differential ... dysmorphic RBC’s, RBC ... throughout (upper urinary ... prostatic) #Diagnosis #EM ... #Differential #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... Myelogenous Leukemia • Primary ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... malignancy #Primary ... diagnosis #workup #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Ducts - PBC ... Transaminitis #Algorithm ... #diagnosis #hepatology
Liver Mass - Differential Diagnosis Algorithm
Cystic:
 • Benign 
     - Simple: Simple
Liver Mass - Differential ... Diagnosis Algorithm ... Malignant - primary ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology