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diagnosis management nephrology differential algorithm pathophysiology pharmacology treatment causes hyponatremia sodium cardiology table clinical comparison syndrome hematology rheumatology toxicology dermatology
EKG CHANGES AS A RESULT OF CHANGES IN NA OR K CHANNEL CONDUCTION - GRAPHIC BY
OF CHANGES IN NA ... Channelopathy #Channels #NaK
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
ultrasound HRS-NAKI
Thiazide diuretics Carbonic anhydrase inhibitors (e.g., acetazolamide) Nat-Cl symport Na and HCO;- reabsorption Aldosterone antagonists (e.g., spironolactone) Nat channel (indirect effect) Loop diuretics (e.g., furosemide) Amiloride, #triamterene Nat-K+-2CF symport Na channel (direct effect) #NaCI reabsorption
acetazolamide) Nat-Cl ... symport Na and ... spironolactone) Nat ... #triamterene Nat-K ... +-2CF symport Na
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management • Giant Cell Arteritis (GCA) •
Takayasu's arteritis (TAK ... Sources: GCA/TAK
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
N-Acetyl Cysteine (NAC ... NAC helps replenish ... Figure 2.1 NAC has ... NAC augments sulfation ... Pathophys #Toxicology #NAC
Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg) Assess Volume Status,
Algorithm (Serum Na ... Status, Check Urine Na
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
Ketoacidosis (AK ... Recall, NAD+ is ... Alcohol depletes NAD ... Patients with AK ... In both SK and AK
Hyponatremia Differential Diagnosis Table • Step 1: Correct for hyperglycemia. Corrected Na = [(glucose - 100)/
Corrected Na = [ ... Urine Osm • Na ... of total body Na
Fetal Yawn on Fetal Ultrasound Baby captured yawning during ultrasound exam. Nap time soon. Robert Jones @RJonesSonoEM #Fetal #Yawn
Nap time soon.
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 Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
GHR activates JAK-STAT ... GHR activates JAK-STAT
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