21 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... • Urine Chloride ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... hypomagnesemia • Metabolic alkalosis ... Hypochloremic metabolic alkalosis ... ratio 0.5%) Differential ... #nephrology #management
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... , Gitelman syndrome ... reabsorption of NaCl ... #urine #Algorithm ... #nephrology #differential
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Transcellular Shift: • Alkalosis ... • Refeeding syndrome ... #nephrology #low
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... - Differential ... Diagnosis Algorithm ... , Gitelman Syndrome ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... , Gitelman syndrom ... #Differential # ... potassium #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... - Differential ... Diagnosis Algorithm ... , Gitelman Syndrome ... #Nephrology #Causes
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... postchronic hypercapnia (acute ... furosemide-like lesion) • Gitelman ... #Differential # ... Diagnosis #Causes #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... - Metabolic Alkalosis ... , Gitelman syndrome ... #differential # ... potassium #nephrology