10 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... Metabolic alkalosis ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... , Gitelman syndrome ... reabsorption of NaCl ... #nephrology #differential ... #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... ratio 0.5%) Differential ... #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... , Gitelman syndrome ... #diagnosis #Algorithm ... #differential # ... potassium #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... postchronic hypercapnia (acute ... furosemide-like lesion) • Gitelman ... #Differential # ... #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Diagnosis Algorithm ... and metabolic alkalosis ... UNa > 20: • Acute ... #Diagnosis #Algorithm ... #Causes #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Pre-Renal: • Hypovolemia ... Abdominal Compartment Syndrome ... Diagnosis #nephrology ... #causes #algorithm
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
↑ Aldosterone: Kidney ... , Gitelman syndrome ... urine #potassium #differential ... #algorithm #diagnosis ... #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Diagnosis Algorithm ... , Acute Respiratory ... Alkalosis, Tumor ... #Diagnosis #Algorithm ... #nephrology #phosphorus
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... diuretic use), Gitelman's ... Hypomagnesemia, Acute ... #Causes #differential ... #diagnosis #nephrology