50 results
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
Stork test) • XR ... — scotty dog sign ... MSK #diagnosis #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Incr CK • Bone marrow ... Complications #pathophysiology ... #signs #symptoms
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... range of potential pathophysiologic ... - Pathophysiology ... Ill-appearing, vital sign ... Targetoid #Algorithm #Differential
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Pathophysiology ... Embolism of marrow ... Syndrome #Diagnosis #Signs
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Osteocytes • Increase Marrow ... #Osteoporosis #pathophysiology ... #signs #symptoms
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... mottled extremities, narrow ... Chest x-ray: signs ... of CXR congestion
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... acid, Elevated Cr
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
the Nikolsky sign ... diagnosis is narrowed ... the Nikolsky sign ... , the differential ... Febrile #Fever #Differential
Diffuse consolidation
The most common cause of diffuse consolidation is pulmonary edema due to heart failure.
This is
cardiogenic edema, to differentiate ... Look for other signs ... Radiology #Pulmonary #CXR ... Consolidation #Differential
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... tissue damage - CXR