13 results
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
antimicrobials, clinical ... factors: - Serology ... antiphospholipid syndrome ... specific pathogens also ... Endocarditis #diagnosis #differential
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Autoimmune (SLE/APLS ... heart valves • MRI ... brain for cerebral ... often seen • MRI ... #Endocarditis #comparison
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Abscess - Differential ... Consider prior antibiotics ... as a cause of a ... Brain: - Streptococcal ... SAPHO, Sweet's Syndrome
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
affecting the Brain ... neuropathy (LHON) plus MRI ... lesions and clinical ... #neurology #noninflammatory ... #differential #
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... + MRI lesions + ... lung nodules, may also ... #differential # ... causes #radiology #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Diagnosis: MRI ... : The clinical ... syndrome of HAD ... reversible • HAND is also ... dementia #AIDS #Neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
parietal lobes of the brain ... may precede the neurologic ... edema visualized as ... Reversible course Differential ... parietal lobes of the brain
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Myotonic dystrophy - Brain ... Generalized fatigue - ALS ... diagnosis #management #neurology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... affected areas and if negative ... - MRI: inflammation ... with acne: antibiotics
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... cellular function Clinical ... MRI: Brain, cervical ... conditions listed in differential ... Lateral #Sclerosis #neurology