10 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... or if a primary hematologic ... #Workup #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... • Reduced liver ... associated with systemic ... #differential #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... ASA) • Renal Disease ... Vascular System ... Iatrogenic) • Liver ... #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... associated with systemic ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Bleeding (64%) • Renal ... DIC • Severe Liver ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
gas on hepatic ultrasound ... portal venous system ... variety of other causes ... #hepatology #liver ... #pocus #clinical
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
performed PT, PTT ... antiglobulin tests - Negative ... the presence of renal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, DIC, hypoTN, renal ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
, DIC, hypoTN, renal ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... cancers, HCC, renal ... gastric tumors • Hematology ... differential #diagnosis #hematology