16 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
- Cytopenia: Common ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... : Chronic disease ... #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
pANCA anti-MPO - Negative ... Usual therapeutic management ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
(FNHTR): Most common ... Causes purpura & ... Related Acute Lung ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
(FNHTR): Most common ... Causes purpura & ... Related Acute Lung ... Transfusions #diagnosis #management ... #hematology #reactions
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
verrucous) • Lung ... • Autoimmune (SLE ... Microbiology: Blood ... • Coagulase-negative ... Endocarditis #diagnosis #management
ECMO Troubleshooting - OnePager Summary
ECMO Emergency Protocol - Team should train/practice & have necessary supplies at
circuit and can cause ... EMBOLISM - can cause ... lung or membrane ... POST-CANNULATION SYNDROME ... #differential #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... disease Caused ... • Dyspnea - Common ... passage • Arterial blood
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Drug Associated (Commonly ... Large Vessel: Blood ... vasculitis, and SLE ... differential #diagnosis #rheumatology