11 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... rash) • Heart, lung ... SJIA], systemic lupus ... #Diagnosis #Management ... #Hematology #Rheumatology
#POCUS of the posterior lung bases in a (#covid19 negative) patient with severe idiopathic pulmonary fibrosis
#POCUS of the posterior ... lung bases in a ... (#covid19 negative ... sonographic interstitial syndrome ... ) #LUS #ultrasound
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... affected areas and if negative ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung ... TRALI): Leading cause ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... Related Acute Lung ... TRALI): Leading cause ... Transfusions #diagnosis #management ... #hematology #reactions
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management