10 results
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... SLE : systemic lupus ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... Management #Summary #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... Negative association ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... differential #diagnosis #algorithm ... #rheumatology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
: Serial negative ... : + (Negative blood ... - Infectious Diseases ... #Endocarditis #comparison ... Marantic #diagnosis #table
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
selected glomerular diseases ... /nephritis • Lupus ... Minimal change disease ... #nephrology #pathology ... #comparison #table
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... deficiency Work ... blood test • Serology ... #Causes #dermatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... joint • Systemic lupus ... ANAs; thus, a negative ... Arthritis #laboratory #workup
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... with previously stable ... patients with a negative ... Renal parenchymal disease ... Neurologic disorders