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diagnosis hematology algorithm management workup causes lupus oncology table anemia erythematosus hemolytic joint leukemia pain pathophysiology platelet product reactions systemic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
infiltrates (anemia, thrombocytopenia ... lymphocytic lymphoma (SLL ... -> Invade Skin: ... Lymphocytic Lymphoma (SLL ... #Leukemia #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Autoimmune • ITP • SLE ... • CLL • APLA ... Algorithm #Causes #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis(5%) Blood ... Leucopenia/lymphopenia, Thrombocytopenia ... symptoms #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... Neutropenia, anemia, thrombocytopenia ... workup #oncology #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... hemostasis: - Thrombocytopenia ... cryoglobulins • Skin ... #Differential # ... Algorithm #Causes #dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Associated - SLE ... #Diagnosis #hematology ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... reticularis Differential ... vasculitis (inflamed blood ... #rash #diagnosis ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... plateletcount), peripheral blood ... test, ANA (e.g., SLE ... not required in all ... Causes #Workup #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... NPSLE rare, Malar rash ... pANCA anti-MPO - Negative ... #comparison #table ... #rheumatology #
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