52 results
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... to maintain a negative ... contraction force (negative ... inotropy) ACCP Cardiology ... Antiarrhythmics #Pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
1 - Sodium Channel ... contraction force (negative ... inotropy) ACCP Cardiology ... Vaughan #Williams #Pharmacology ... pathophysiology #cardiology
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium Channel ... #Blockers #ClassI ... #Na #cardiology ... #pharmacology # ... table #comparison
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
to the sodium-channel ... voltage-sensitive calcium channels ... #Pathophys #Pharmacology ... #Cardiology #Antiarrhythmics ... #Classes #Effect
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Classification Class ... Ib, Ic) - Na+ Channel ... III - K+ Channel ... IV - Ca2+ Channel ... #cardiology #pharmacology
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
Calcium Channel ... CCBs #Calcium #Channel ... NonDihydropyridines #pharmacology ... #comparison #table ... #cardiology
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
and their Key Pharmacologic ... Block fast Na+ channels ... on EKG • Na+ channel ... #Pharmacology # ... Agents #Cardiology
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... #differential # ... #culture #negative ... InfectiousDiseases #Microbiology ... #CNIE #BCNIE #cardiology
Causes of Drug-Induced Cardiomyopathies

#DrugInduced #Medications #Cardiomyopathy #Cardiomyopathies #Differential #Causes #Cardiology #Pharmacology
Causes of Drug-Induced ... Cardiomyopathies #Differential ... #Causes #Cardiology ... #Pharmacology
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
- Antibiotics Class ... transmembrane channels ... No gram negative ... cidal nature) #Pharmacology