11 results
Running out of Analgesia and Sedation Medications due to #COVID19?  Anand Swaminathan, MD has put
options in REBEL Review ... #97: Sedation and ... #sedative #analgesia ... #pharmacology # ... alternatives #Drugs
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Rapidly cidal drug ... No gram negative ... cidal nature) #Pharmacology ... #Antibiotics #Review
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Sedative-Hypnotic ... depression with sedative-hypnotic ... drugs #Sedative ... #medications #pharmacology ... #comparison #table
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
) - Antibiotics ... No gram negative ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
. aerobic gram negatives ... for: hospital acquired ... due to gram-negative ... #Pharmacology #Antibiotics ... #Review #Overview
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
coverage, some gram negative ... suspect community-acquired ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
and most Gram negatives ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics ... #Review #Overview
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview

50S Ribosomal Inhibitor (PO and IV)
Spectrum: Atypical organisms
and some gram negatives ... exacerbations, community-acquired ... Used for MAC treatment ... #Pharmacology #Antibiotics ... #Review #Overview
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... screening: High negative ... 96.1% • Empiric antibiotic ... #Pulmonary #Community ... #Acquired
Anti-Pseudomonal - Antibiotics Class Overview

Pseudomonas aeruginosa is a non-fermenting Gram-negative bacillus that inhabits a variety of
Anti-Pseudomonal - Antibiotics ... non-fermenting Gram-negative ... empiric Pseudomonas treatment ... Polymyxin B(IV) #Pharmacology ... #Antibiotics #Review