6507 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
C3 positive or negative ... mediated - DAT: IgG negative ... Pathophysiology #diagnosis ... #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
- Differential Diagnosis ... AIHA (7-8%) DAT-negative ... #Differential #Diagnosis ... #Table #hematology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
Hemolysis DAT Negative ... Autoimmune #Hemolysis #hematology ... #diagnosis
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... normal • DAT negative ... #Differential #Diagnosis ... Management #Algorithm #hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
- Differential Diagnosis ... Bacteria • Gram Negative ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- negative ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... bacilliformis: - Gram negative ... Nodular → Mular DIAGNOSIS ... #Oroya #Fever #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... antiglobulin tests - Negative ... ThromboticThrombocytopenicPurpura #Diagnosis ... #Workup #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Diagnosis ... levels >1g/L • Negative ... cryoglobulins • Negative ... Cryofibrinogenemia #diagnosis ... hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... for anti-C3d and negative ... Differential Diagnosis ... hemolytic #anemia #hematology ... #diagnosis