23 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... pANCA anti-MPO - Negative
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... pANCA anti-MPO - Negative
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... erythematosus #signs
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... evidence of (fatigue, rash ... Photosensitive rash ... permanent alopecia Differential ... Clinical Features
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... painless, no systemic signs ... biopsy preferred Differential ... Sporotrichiosis #Infection #clinical ... #photo #hand
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... Clinical Presentation ... Petechial or purpuric rash ... SJIA], systemic lupus ... #Diagnosis #Management
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... patients with a negative ... hypertension and signs ... 109 mm Hg) with clinical ... renal bruit or signs
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Maculopapular rash ... • Common clinical ... Acute meningeal signs ... in 70%-85% • Negative ... • Uveitis • Rash
Bradycardia
1) First Steps: IV, O2, Monitors, ECG, Pads on patient, Crash Cart in room. Is patient
Pads on patient, Crash ... worsening brady, Signs ... Administer sedative ... bradycardia #diagnosis #differential ... #management #cardiology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... purpura: strong sign