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diagnosis infectiousdiseases endocarditis cardiology causes bcnie betadglucan culture galactomannan infective microbiology transplant abscess bacteria biomarkers blood bloodculture chest clinical cnie
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture Negative ... Abscess - Differential ... as a cause of a negative ... AnnKumfer #Culture #Negative ... #Abscess #Differential
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
bacilli - Fungi ... (Candida, Aspergillus ... ) - Culture negative ... bacilli - Fungi ... Pathogens #Diagnosis #Differential
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
Important Fungal ... and chitin in fungal ... exceptions are Aspergillus ... • India ink - "Negative ... #fungus #comparison
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Coccidioides - Negative ... Cryptococcus - Negative ... BAL GM does not differentiate ... Galactomannan #diagnosis #comparison
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Staphylococci (skin), Gram-negative ... Staphylococci (skin), Gram-negative ... (mucosa), Aspergillus ... : Aspergillus spp ... Infections #Timeline #differential
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
Simple Virus • Fungal ... Cryptococcus Neoformans, Aspergillus ... cell carcinoma (native ... Renal #Transplant #differential ... urine #management #treatment
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... BCNIE #Causes #differential ... causes #culture #negative
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... Almost always negative ... in BAL does not differentiate ... closely related fungi ... Galactomannan #Fungal
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... fastidious bacteria or fungi ... (Aspergillus, Candida ... Endocarditis #diagnosis #differential
Causes of Myocarditis 1. Infectious Myocarditis • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
Weil disease) • Fungal ... - Aspergillus, ... Autoantigens - Infection-negative ... lymphocytic, infection-negative ... Myocarditis #Causes #differential
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