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rheumatology erythematosus joint arthritis systemic activation approach classification clues comparison dermatology druginduced macrophage mas monoarthritis monoarticular myelitis neurology oligoarthritis oligoarticular
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Rash • Human ... infection Malar rash ... lesions • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... pANCA anti-MPO - Negative ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... pANCA anti-MPO - Negative ... #table #rheumatology ... #diagnosis #management
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... everywhere) 2) A rash ... the face (many differential ... #diagnosis #sle
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... Arthritis: • Joint pain
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Arthritis Differential ... Diagnosis Framework ... aureus • Gram-negative ... #Differential # ... Diagnosis #MSK #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... Petechial or purpuric rash ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... approach #workup #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... vasculitis, and SLE ... #diagnosis #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... tested and if negative ... Disorders: - SLE ... #management #neurology ... #differential
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