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Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... likelihood of negative ... clinical outcomes ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Coccidioides - Negative ... infection (IFI) in hematologic ... cut-offs defined in clinical ... Cryptococcus - Negative ... BAL GM does not differentiate
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... for anti-C3d and negative ... younger pts) Differential ... hemolytic #anemia #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... AIHA (7-8%) DAT-negative ... #Anemia #AIHA #Differential ... Diagnosis #Table #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Pancytopenia - Differential ... Infiltration: • Hematologic ... and non-hematologic ... #Neutropenia #Differential ... Algorithm #Causes #Hematology
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
epidermidis - Gram-negative ... ) - Culture negative ... Enterococci - Gram-negative ... streptococci - Culture negative ... Pathogens #Diagnosis #Differential
Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve
Systemic infection Native ... HACEK • Culture-negative ... epidermidis • Gram-negative ... Enterococcus • Gram-negative ... Noninfective #Causes #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Non malignant hematologic ... states • Non-hematologic ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... normal • DAT negative ... Microangiopathy #TMA #Differential ... Management #Algorithm #hematology
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