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Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework NCPE Pathophysiology: Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Edema - Differential ... • Normal or negative ... pg/ml EKG: • Negative ... infarction • Gram negative ... #edema #NCPE #differential
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Presentation (Pulmonary ... symptomatology Differential ... polyangiitis) - ANCA-negative ... Renal #Syndrome #differential
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Infancy (SUDI) - Differential ... Neurologic Anomaly • Pulmonary ... ): • Autopsy negative ... Infancy #Infant #Differential
Approach to the Hypotensive Patient - Differential Diagnosis Framework for Hypotension Blood Pressure = Heart Rate x
Hypotensive Patient - Differential ... depletion • Pulmonary ... stenosis • Meds: negative ... #hypotensive #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
With associated pulmonary ... Pauci-immune mediated (Negative ... Glomerulonephritis #Vasculitis #differential
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
Hemopericardium)- Differential ... patients with pulmonary ... may have false negative ... Hemopericardium #Differential
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
epidermidis - Gram-negative ... ) - Culture negative ... Enterococci - Gram-negative ... streptococci - Culture negative ... Pathogens #Diagnosis #Differential
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
- Overview and Differential ... aureus, Coagulase-negative ... staphylococci Culture Negative ... Cerebral > Splenic, Pulmonary ... #Endocarditis #Differential
Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve
Systemic infection Native ... HACEK • Culture-negative ... epidermidis • Gram-negative ... Enterococcus • Gram-negative ... Noninfective #Causes #Differential
Important Biostatistics and Epidemiology Equations Sensitivity = TP / (TP + FN) = true positives / disease
FP + TN) = true negatives ... all positives Negative ... FN + TN) = true negatives ... / all negatives ... Specificity) Negative
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