9 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... pANCA anti-MPO - Negative ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
it should not cause ... dissociative drug, it causes ... 0.5mg x1) for nausea ... #CriticalCare # ... diagnosis #management
ICU Pre-Rounding Bundle Checklist
VITALS: trends!
 • Important to know if the pt is getting better or
ICU Pre-Rounding ... and hourly net negative ... / TUBES: know gauges ... Bundle #Checklist #CriticalCare ... #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
The ECF and ICF ... making it more negative ... K+ in the ECF causes ... #foamed #criticalcare ... #management #diagnosis
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
have achieved negative ... the determined cause ... differential #algorithm #management ... heartfailure #chf #criticalcare ... #icu #clinical