19 results
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
valves • MRI brain ... in up to 30% of cases ... common, Aortic root abscess ... often seen • MRI brain ... large infarct - Infectious
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... Negative Abscess ... antibiotics as a cause ... Brain: - Streptococcal ... #Diagnosis #InfectiousDiseases
Major Brain Complications of Endocarditis
Abscess:
 • May be macro or micro and occur at site of
of Endocarditis ... Abscess: • May ... reaction to blood & infectious ... Ischemic stroke caused ... #neurological #neurology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... injury • Infectious ... Encephalitis, Brain ... Abscess, Toxoplasmosis ... #neurology
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
• Typhus, gram-negative ... • Abscess, bacteremia ... Causes: • Still's ... • Hepatic abscess ... Liver or lung abscess
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Infective Endocarditis ... but important causes ... factors: - Serology ... #Infective #Endocarditis ... differential #workup #infectiousdiseases
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... • Coagulase-negative ... Septic Emboli Cause ... Treat underlying cause
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
multiple lesions Infectious ... Syphilis • Pyogenic Abscess ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
aureus, Coagulase-negative ... staphylococci Culture Negative ... Septic emboli cause ... Treat underlying cause ... Diagnosis #cardiology #infectiousdiseases
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... phenomena from endocarditis ... #Lung #Infections ... Differential #Diagnosis #causes ... #infectiousdiseases