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diagnosis management differential rheumatology infections syndrome aids alkaline alp cerebritis coagulation dic disseminated encephalopathy erythematosus fungal hepatology hiv hyophosphatasia intravascular
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... #neurology #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Antimicrobial treatment ... Demyelinating disease ... caused by the JC ... opportunistic #InfectiousDiseases ... #Neurology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Bleeding (64%) • Renal ... Thromboembolism (7%) • CNS ... • Severe Liver Disease ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
membrane into the CNS ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... : - Renal failure
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... tested and if negative ... • Infectious causes ... Transverse Myelitis Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... • Treatment of
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... chorioretinitis, CNS
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
extrapulmonary disease ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases
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