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management diagnosis rheumatology differential hivaids infections opportunistic prevention sle erythematosus neurology systemic algorithm antimicrobials capsulatum cardiology cerebritis cns comparison dosing
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... Puncture, EEG Treatment ... diagnosis #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
IDSA - Clinical Strategy to Build an Individualized Treatment Regimen for Multi-Drug Resistant Tuberculosis (MDR-TB) •
IDSA - Clinical ... Individualized Treatment ... children with TB disease ... antimicrobials #regimens #pharmacology ... #dosing #idsa #
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... tested and if negative ... • Infectious causes ... MCTD - Bechet disease ... Transverse Myelitis Treatment
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
aureus, Coagulase-negative ... staphylococci Culture Negative ... Septic emboli cause ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS Pre-Exposure Prevention of VZV
IDSA Recommendations ... confirmation of disease ... Uncomplicated Cases ... #Zoster #VZV #IDSA ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS Preventing Chronic Microsporidiosis: • Because chronic microsporidiosis occurs
IDSA Recommendations ... should prevent the disease ... Gastrointestinal Infections Caused ... Microsporidiosis #IDSA ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
IDSA Recommendations ... histoplasmosis (>10 cases ... Severe Disseminated Disease ... #Prevention #Treatment ... infections #HIVAIDS #pharmacology
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