17 results
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... to maintain a negative ... #Pharmacology # ... #pathophysiology
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics ... EricsMedicalLectures/ #Antiarrhythmics ... Channel #Blockers #ClassI ... Na #cardiology #pharmacology ... #table #comparison
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Antiarrhythmics ... contraction force (negative ... accpcardprn #Antiarrhythmics ... Vaughan #Williams #Pharmacology ... #pathophysiology
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
Class I Antiarrhythmics ... and their Key Pharmacologic ... depolarization (phase ... #Class1 #Antiarrhythmics ... #Pharmacology #
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
show different relative ... of estrogen to negatively ... , progesterone causes ... #OvarianCycle #pathophysiology ... #comparison #endocrinology
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
Plasma-Lyte - Causes ... - Causes lactic ... removed- trials were negative ... #Crystalloids #pharmacology ... #indications #comparison
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
serology: Serial negative ... Frequent false-negative ... cultures/serology: + (Negative ... in up to 30% of cases ... #Endocarditis #comparison
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... rate (lengthens phase ... 4 and phase O of ... #Pathophysiology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Bradyarrhythmias, Some cases ... Vasopressors #Inotropes #comparison ... #table #pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... druginduced #lupus #sle #comparison