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diagnosis differential cardiology culture clinical infectiousdiseases infective management table abscess bacteria bcnie blood capnocytophaga catarrhalis children cnie etiology fungal fungi
Infective endocarditis - etiology and sources of infection. • Native and prosthetic valve endocarditis •
Infective endocarditis ... • Native and ... prosthetic valve endocarditis ... #Sources #Causes ... #Differential #Microbiology
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... #culture #negative ... #Endocarditis # ... InfectiousDiseases #Microbiology
Streptocccus Pneumoniae Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative Epidemiology - 10% adult carriers: • Most common cause of:
Streptocccus Pneumoniae Microbiology ... Alpha-hemolytic, Catalase Negative ... • Most common cause ... media • Important cause ... peritonitis, and endocarditis
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
serology: Serial negative ... Frequent false-negative ... cultures/serology: + (Negative ... in up to 30% of cases ... #comparison #infective
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS) Microbiology ... positive in 90% of IE cases ... • Coagulase-negative ... Septic Emboli Cause ... Treat underlying cause
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
• India ink - "Negative ... Fungal #Stains #microbiology ... #microscopy #staining ... fungi #fungus #comparison
Moraxella catarrhalis on culture and microscopy Only 1-5% of adults are colonized with this Gram neg diplococci
on culture and microscopy ... It can be the cause ... Neissseria spp. negative ... ) - Gram negative ... #clinical #microbiology
Capnocytophaga spp on Culture and Blood Smear Associated w/ dog/human oral flora, can cause bacteremia in immunocompromised
oral flora, can cause ... anaerobe; narrow Gram negative ... Smear #clinical #microscopy ... #microbiology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS) Microbiology ... aureus, Coagulase-negative ... staphylococci Culture Negative ... Septic emboli cause ... Treat underlying cause
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Common bacterial causes ... • Enteric gram negative ... from contiguous focus ... artery (e.g., endocarditis
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